In Vitro Antibacterial Activity and Phytochemical Evaluation of Acanthospermum hispidum (Asteraceae) Root Extracts

Authors

  • Abdulmalik, H. G. Usmanu Danfodiyo University, Sokoto
  • Umar, Z. F. Usmanu Danfodiyo University, Sokoto
  • Mohammed, M. L, Usmanu Danfodiyo University, Sokoto
  • Mshelia, E. H. Usmanu Danfodiyo University, Sokoto
  • Dauda, J. A, Usmanu Danfodiyo University, Sokoto
  • Abdulrahim, H. J. Usmanu Danfodiyo University, Sokoto
  • Umar, R. Federal University of Technology Minna
  • Yahaya, S. M. Usmanu Danfodiyo University, Sokoto
  • Dahiru, H. Usmanu Danfodiyo University, Sokoto
  • Victor, C. U. Federal University Gusau

Keywords:

Acanthospermum, Extraction, Phytochemical, Antibacterial, Activity

Abstract

Acanthuspermum hispidum (Astereceae) is used in traditional medicine for the treatment of microbial infections. This research was designed to investigate the phytochemicals and antibacterial potentials of the root extract of A. hispidum. The powdered root was sequentially extracted by soxhlet extractor using n-hexane, chloroform and methanol. Antibacterial profile of the crude extracts were examined against clinical isolates of the following bacterial; Escherichia coli 0:157:H7, Streptococcus Pneumonia, Methicilin resistant Staphylococcus aureus (MRSA) and Mannheim species using standard procedures. The chloroform crude extract show higher activity against all tested organisms with zone of inhibition ranging from 13-30mm at 12.5-100mg/mL concentration. The activity demonstrated can be compared with that of ciprofloxacin at 20 mg/mL with the zone of inhibition ranging between 30-35mm on the organism tested. The phytochemical evaluation reveals the present of the following metabolites; steroids, tannins, flavonoid, alkaloid, cardiac glycoside and saponins. Acanthospermum hispidum possessed antibacterial activity which resided in the chloroform
extract of the root.

Author Biographies

Abdulmalik, H. G., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Umar, Z. F., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Mohammed, M. L,, Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Mshelia, E. H., Usmanu Danfodiyo University, Sokoto

Department of Pharmacognosy and Ethnopharmacy, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Dauda, J. A,, Usmanu Danfodiyo University, Sokoto

Department of Pharmacognosy and Ethnopharmacy, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Abdulrahim, H. J., Usmanu Danfodiyo University, Sokoto

Department of Biological Science, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Umar, R., Federal University of Technology Minna

Department of Crop Production, Federal University of Technology Minna, Nigeria, West Africa

Yahaya, S. M., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa.

Dahiru, H., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University Sokoto, Sokoto State, Nigeria, West Africa

Victor, C. U., Federal University Gusau

Department of Microbiology, Federal University Gusau, Zamfara State, Nigeria, West Africa

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Published

2020-10-08

How to Cite

Abdulmalik, H. G., Umar, Z. F., Mohammed, M. L, Mshelia, E. H., Dauda, J. A, Abdulrahim, H. J., Umar, R., Yahaya, S. M., Dahiru, H., & Victor, C. U. (2020). In Vitro Antibacterial Activity and Phytochemical Evaluation of Acanthospermum hispidum (Asteraceae) Root Extracts. International Journal of Science for Global Sustainability, 6(3), 7. Retrieved from https://fugus-ijsgs.com.ng/index.php/ijsgs/article/view/77

Issue

Vol. 6 No. 3 (2020): INTERNATIONAL JOURNAL OF SCIENCE FOR GLOBAL SUSTAINABILITY (IJSGS)

Section

Articles